Peripheral Tissue Oxygenation During Standard and Miniaturized Cardiopulmonary Bypass (Direct Oxymetric Tissue Perfusion Monitoring Study)

Peripheral tissue oxygenation during standard CPB and miniaturized CPB (direct oxymetric tissue perfusion monitoring study).

AIM The aim of this study was to compare the impact of standard cardiopulmonary bypass (CPB) with mini CPB on peripheral tissue perfusion. METHODS 24 patients with ischemic heart disease scheduled for CPB were randomised to two groups: Group A (12 patients, standard CPB) and Group B (12 patients, mini CPB). Oxygen tension was measured with an optical multiparametric sensor inserted into the p...

Tissue oxygenation response to mild hypercapnia during cardiopulmonary bypass with constant pump output.

BACKGROUND Tissue oxygenation is the primary determinant of wound infection risk. Mild hypercapnia markedly improves cutaneous, subcutaneous (s.c.), and muscular tissue oxygenation in volunteers and patients. However, relative contributions of increased cardiac output and peripheral vasodilation to this response remains unknown. We thus tested the hypothesis that increased cardiac output is the...

Extracorporeal membrane oxygenation (ECMO): prolonged bedside cardiopulmonary bypass.

The History of Goal-Directed Therapy and Relevance to Cardiopulmonary Bypass.

Goal-directed therapy is a patient care strategy that has been implemented to improve patient outcomes. The strategy includes aggressive patient management and monitoring during a period of critical care. Goal-directed therapy has been adapted to perfusion and has been designated goal-directed perfusion (GDP). Since this is a new concept in perfusion, the purpose of this study is to review goal...

Esophageal saturation during antegrade cerebral perfusion: a preliminary report using visible light spectroscopy.

BACKGROUND Visible light spectroscopy (VLS) is newer technology that measures real-time tissue oxygenation. It has been validated in detecting mucosal ischemia in adults. During complex neonatal heart surgery, antegrade cerebral perfusion (ACP) maintains cerebral saturation. Whether ACP maintains peripheral tissue perfusion in humans is not known. METHODS Five patients undergoing neonatal ope...